Research Article

Exosome-Derived Circ_0094343 Promotes Chemosensitivity of Colorectal Cancer Cells by Regulating Glycolysis via the miR-766-5p/TRIM67 Axis

Figure 6

miR-766-5p targets TRIM67. (a) TargetScan website predicted the targeting sequences of miR-766-5p and TRIM67; (b) DLR gene assay verified the targeting relationship between circ_0094343 and miR-766-5p; (c) qRT-PCR measured TRIM67 expression level in the CRC tissue and adjacent tissue; (d), (e) Pearson correlation analysis analyzed the correlation between miR-766-5p and TRIM67 expression in CRC tissue (d) as well as the association between circ_0094343 and TRIM67 expression (e); (f) qRT-PCR determined the expression level of miR-766-5p and TRIM67 in HCT116 cells after miR-766-5p mimics and mimicked NC treatment; (g), (h) Western blot for detection of the protein expression level of TRIM67 in HCT116 cells after miR-766-5p mimics and mimics NC treatment; (i) qRT-PCR detected the expression level of TRIM67 in cells of each group. .
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