Research Article

Long Noncoding RNA CASC2 Facilitated Wound Healing through miRNA-155/HIF-1α in Diabetic Foot Ulcers

Figure 3

LncRNA CASC2 directly targeting miR-155. (a) Sequence alignment of the binding site between lncRNA CASC2 and miR-155. (b) The experiment of the dual-luciferase reporter gene detected the fluorescence activity of lncRNA CASC2-wt/mut under the treatment of miR-155/NC mimics, vs. group of CASC2-wt + NC mimics. (c) The lncRNA CASC2 expression, preferably after miR-155 mimics/inhibitor transfection, was performed by RT-qPCR, against a group of NC mimics and against a group of NC inhibitor.
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