The Diagnostic Value of 18F-FDG PET/CT Bone Marrow Uptake Pattern in Detecting Bone Marrow Involvement in Pediatric Neuroblastoma Patients
Table 2
Clinical characteristics of different18F-FDG PET/CT bone marrow uptake patterns.
Total
BMUP1
BMUP2
BMUP3
BMUP4
Age
3.53 ± 2.17
2.97 ± 3.08
3.98 ± 2.57
2.42 ± 1.31
4.45 ± 2.02
＜0.001
Gender
Female
50 (51.0%)
7 (77.8%)
5 (41.7%)
19 (54.3%)
19 (45.2%)
0.316
Male
48 (49.0%)
2 (22.2%)
7 (58.3%)
16 (45.7%)
23 (54.8%)
Primary site
Chest
13 (13.3%)
6 (66.7%)
1 (8.3%)
2 (5.7%)
4 (9.5%)
＜0.001
Abdomen
82 (83.6%)
3 (33.3%)
11 (91.7%)
30 (85.7%)
38 (90.5%)
Pelvic
3 (3.1%)
0 (0.0%)
0 (0.0%)
3 (8.6%)
0 (0.0%)
INRGSS
L1
11 (11.2%)
0 (0.0%)
0 (0.0%)
11 (31.4%)
0 (0.0%)
＜0.001
L2
17 (17.3%)
5 (55.6%)
0 (0.0%)
12 (34.3%)
0 (0.0%)
M
68 (69.4%)
4 (44.4%)
12 (100.0%)
10 (28.6%)
42 (100.0%)
c
2 (2.1%)
0 (0.0%)
0 (0.0%)
2 (5.7%)
0 (0.0%)
INRGCS
Extremely low risk
12 (13.2%)
0 (0.0%)
0 (0.0%)
12 (37.5%)
0 (0.0%)
<0.001
Low risk
6 (6.6%)
4 (57.1%)
0 (0.0%)
2 (6.3%)
0 (0.0%)
Medium risk
11 (12.1%)
2 (28.6%)
1 (9.1%)
7 (21.9%)
1 (2.4%)
High risk
62 (68.1%)
1 (14.3%)
10 (90.9%)
11 (34.3%)
40 (97.6%)
INRGSS: International Neuroblastoma Risk Group Staging System; INRGCS: International Neuroblastoma Risk Group Classification System; BMUP: bone marrow uptake pattern; BMUP1: direct invasion; BMUP2: focal/multifocal uptake; BMUP3: diffuse and homogeneous uptake; BMUP4: diffuse and heterogeneously uptake; .
