Dynamic Total-Body PET/CT Imaging Reveals Kinetic Distribution of ⁶⁸Ga-DOTATATE in Normal Organs

Table 2

Summary statistics of K₁ and k₂ in normal organs.

Tissues	Site	K1 (min^−1)						k2 (min^−1)
		Mean ± SD	CV (%)	Intersite var. (%)	P	Intersubject var. (%)	P	Mean ± SD	CV (%)	Intersite var. (%)	P	Intersubject var. (%)	P
Nasal mucosa	Av.	0.0572 ± 0.0361	63.2	1.65	0.662	73.53	0.075	0.1025 ± 0.1209	118.0	3.86	0.501	57.45	0.282
	L	0.0507 ± 0.0255	50.3					0.2474 ± 0.5207	210.5
	R	0.0577 ± 0.0323	56.0					0.1088 ± 0.0873	80.3
Cerebrum	Av.	0.2102 ± 0.071	33.8	4.47	0.468	69.84	0.110	5.4444 ± 2.1166	38.9	3.81	0.503	75.95	0.056
	L	0.2058 ± 0.0639	31.0					4.4487 ± 1.8598	41.8
	R	0.1831 ± 0.0484	26.5					3.7579 ± 1.8874	50.2
Pituitary		0.1866 ± 0.0425	22.8	–	–	–	–	0.3077 ± 0.8121	264.0	–	–	–	–
Parotid	Av.	0.186 ± 0.1476	79.4	1.35	0.626	77.30	0.073	0.9824 ± 1.7906	182.3	1.71	0.656	65.85	0.156
	L	0.1456 ± 0.0605	41.6					0.404 ± 0.3437	85.1
	R	0.1604 ± 0.0456	28.4					0.49 ± 0.3606	73.6
SMG	Av.	0.2996 ± 0.1646	54.9	6.95	0.362	65.81	0.157	0.7484 ± 0.5908	78.9	0.00	0.998	47.99	0.456
	L	0.2538 ± 0.0998	39.3					0.9123 ± 0.8845	97.0
	R	0.3287 ± 0.1838	55.9					0.9133 ± 0.727	79.6
Thyroid	Av.	0.6024 ± 0.3092	51.3	18.85	0.121	63.64	0.186	1.5922 ± 1.0735	67.4	22.29	0.088	56.11	0.305
	L	0.6629 ± 0.2083	31.4					1.7479 ± 0.5792	33.1
	R	0.4949 ± 0.1657	33.5					1.2023 ± 0.5193	43.2
Liver	Av.	0.2688 ± 0.0888	33.0	26.45	0.057	17.83	0.609	0.0926 ± 0.0879	95.0	21.69	0.112	38.74	0.082
	LL	0.1775 ± 0.0844	47.5					0.0369 ± 0.0286	77.6
	RU	0.2445 ± 0.0388	15.9					0.1235 ± 0.1154	93.5
	RM	0.2322 ± 0.0513	22.1					0.0506 ± 0.0359	71.0
	RL	0.2706 ± 0.061	22.5					0.0658 ± 0.0538	81.7
Spleen		0.4864 ± 0.1385	28.5	–	–	–	–	0.0174 ± 0.0282	162.5	–	–	–	–
Pancreas	Av.	0.7439 ± 0.3157	42.4	6.21	0.390	67.35	0.138	1.9608 ± 0.951	48.5	27.30	0.055	54.38	0.336
	Head	0.5484 ± 0.4866	88.7					0.7274 ± 1.0659	146.5
	Body	0.7409 ± 0.2997	40.5					1.8315 ± 0.8705	47.5
Kidney	Av.	1.1767 ± 0.255	21.7	3.08	0.548	72.63	0.083	0.3823 ± 0.3048	79.7	7.17	0.355	60.22	0.237
	L	1.21 ± 0.4338	35.9					0.4786 ± 0.6549	136.8
	R	1.0975 ± 0.2092	19.1					0.2372 ± 0.1046	44.1
Adrenal	Av.	0.3657 ± 0.0835	22.8	5.32	0.428	33.97	0.725	0.1085 ± 0.2728	251.4	0.37	0.837	42.90	0.556
	L	0.4523 ± 0.2789	61.7					0.2766 ± 0.7318	264.6
	R	0.3618 ± 0.085	23.5					0.2047 ± 0.5281	258.0
Prostate		0.139 ± 0.0312	22.5	–	–	–	–	0.0594 ± 0.0696	117.1	–	–	–	–
Bone		0.1532 ± 0.0621	40.5	–	–	–	–	0.5601 ± 0.2665	47.6	–	–	–	–

SMG, submandibular gland; SD, standard deviation; CV, coefficient of variance; var., variance; Av., average; L, left; R, right; LUL, left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; RU, right upper area, RM, right middle area; RL, right lower area; LL, left lobe.