Dynamic Total-Body PET/CT Imaging Reveals Kinetic Distribution of ⁶⁸Ga-DOTATATE in Normal Organs

Table 3

Summary statistics of k₃ and vB in normal organs.

Organs	Site	k3 (min^−1)						vB						Mean R^2
		Mean ± SD	CV (%)	Intersite var. (%)	P	Intersubject var. (%)	P	Mean ± SD	CV (%)	Intersite var. (%)	P	Intersubject var. (%)	P
Nasal mucosa	Av.	0.0771 ± 0.0747	96.9	10.35	0.262	42.75	0.559	0.0009 ± 0.0017	180	5.56	0.421	50.00	0.424	0.934
	L	0.7275 ± 1.427	196.1					0.0013 ± 0.0022	171.1					0.904
	R	0.0921 ± 0.0623	67.6					0.0005 ± 0.001	185.4					0.887
Cerebrum	Av.	0.0718 ± 0.0289	40.2	15.87	0.158	68.89	0.120	0.0021 ± 0.0055	264.6	7.21	0.352	45.92	0.497	0.782
	L	0.0747 ± 0.0236	31.6					0.0001 ± 0.0003	265.7					0.726
	R	0.0563 ± 0.0223	39.6					0.0034 ± 0.009	264.6					0.681
Pituitary		1.5915 ± 2.295	144.2	–	–	–	–	0.0195 ± 0.0304	155.6	–	–	–	–	0.933
Parotid	Av.	0.2817 ± 0.3589	127.4	2.01	0.629	69.19	0.117	0.0068 ± 0.0069	102.2	1.16	0.727	74.42	0.064	0.972
	L	0.1685 ± 0.1274	75.6					0.0037 ± 0.0041	111.2					0.953
	R	0.2014 ± 0.1209	60.0					0.0044 ± 0.0034	76					0.948
SMG	Av.	0.2091 ± 0.166	79.4	0.17	0.889	39.10	0.630	0.0233 ± 0.03	128.9	7.90	0.331	75.98	0.056	0.918
	L	0.2606 ± 0.3396	130.3					0.0326 ± 0.0309	94.7					0.866
	R	0.2397 ± 0.1849	77.1					0.0176 ± 0.0241	136.9					0.892
Thyroid	Av.	0.2263 ± 0.1471	65.0	7.94	0.329	72.41	0.084	0.0152 ± 0.0255	168.1	0.50	0.810	54.74	0.329	0.907
	L	0.1631 ± 0.0688	42.2					0.0176 ± 0.0153	86.9					0.833
	R	0.2204 ± 0.1322	60.0					0.0202 ± 0.0243	120					0.867
Liver	Av.	1.2921 ± 2.9613	229.2	6.71	0.637	37.47	0.097	0.0039 ± 0.0104	264.6	5.53	0.707	20.43	0.514	0.988
	LL	1.9039 ± 2.9912	157.1					0.0218 ± 0.0576	264.6					0.974
	RU	1.3334 ± 2.8644	214.8					0.0038 ± 0.01	264.5					0.974
	RM	1.2876 ± 2.9594	229.8					0.0147 ± 0.0389	264.6					0.974
	RL	0.1606 ± 0.1365	85.0					0.0027 ± 0.0072	264.6					0.972
Spleen		0.0929 ± 0.116	124.8	–	–	–	–	0.014 ± 0.024	171.6	–	–	–	–	0.988
Pancreas	Av.	0.246 ± 0.1184	48.1	4.12	0.486	54.43	0.335	0.0355 ± 0.0442	124.5	28.16	0.051	50.29	0.412	0.906
	Head	0.3371 ± 0.472	140.0					0.1627 ± 0.1669	102.6					0.834
	Body	0.206 ± 0.0999	48.5					0.0222 ± 0.0389	174.9					0.751
Kidney	Av.	0.1376 ± 0.1467	106.6	9.48	0.284	50.44	0.409	0.0076 ± 0.0099	129.9	15.63	0.161	71.94	0.089	0.930
	L	0.1424 ± 0.2001	140.5					0.0084 ± 0.0078	93.4					0.908
	R	0.0573 ± 0.0159	27.8					0.0035 ± 0.0036	102.5					0.900
Adrenal	Av.	3.3792 ± 3.0917	91.5	3.29	0.535	61.95	0.210	0.0862 ± 0.0569	66.1	27.00	0.057	54.49	0.334	0.964
	L	4.6309 ± 4.1563	89.8					0.0802 ± 0.1077	134.2					0.946
	R	3.3129 ± 3.5319	106.6					0.2489 ± 0.1824	73.3					0.896
Prostate		1.5535 ± 3.362	216.4	–	–	–	–	0.0076 ± 0.0171	223.6	–	–	–	–	0.945
Bone		0.1517 ± 0.0441	29.1	–	–	–	–	0.0089 ± 0.0077	85.8	–	–	–	–	0.807

SMG, submandibular gland; SD, standard deviation; CV, coefficient of variance; var., variance; Av., average; L, left; R, right; LUL, left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; RU, right upper area, RM, right middle area; RL, right lower area; LL, left lobe.