In the past decades, there has been significant interest in the development of nanoparticles as contrast agents to noninvasively study structural and functional aspects of living organisms. In addition to intrinsic properties such as magnetism or fluorescence that allow their detection by multiple imaging techniques, these particles may also be associated with different molecules or cells to provide targeted imaging of biological processes. Nanoparticles have been applied in investigations in diverse areas including inflammation, infection, neuroscience, cardiology, and oncology. Particularly interesting are the multifunctionalization possibilities of nanoparticles, opening up their use in hybrid molecular imaging experiments that combines functional and structural information. However, continuous research is necessary to improve the knowledge on the safety and potential applications of nanoparticles in biomedical imaging. Furthermore, it is important for researchers to be aware of technical and regulatory challenges in order to adequately translate findings from basic and preclinical reports to the clinical field.

Therefore, we invite the submission of original and review articles on basic, translational, and clinical studies concerning the development and application of nanoparticles.

Potential topics include but are not limited to the following:

• Ultrasound and photoacoustic imaging
• Fluorescence and bioluminescence imaging
• SPECT and PET
• CT and MRI
• PET/MRI
• MPI