Quantitative Measurements in 3-Dimensional Datasets of Mouse Lymph Nodes Resolve Organ-Wide Functional Dependencies
Images of PLNs from wildtype (a), (c), and (e) and plt/plt mutant mice (b) and (d), (f). HEV, red; DCs, green. (a), (b) Maximum-value projections through the voxel data sets. The inset in (a) shows a higher magnification of the region indicated. White arrowheads show the approximate positions of the afferent lymphatic vessels through which the DCs enter the PLNs. (c) and (d) Representative optical slices through the central regions of the lymph nodes shown in (a) and (b). (e) and (f); surface renderings of the data in (a) and (b).