Review Article

Linear and Nonlinear Heart Rate Variability Indexes in Clinical Practice

Table 2

Most used HRV measures. (modified from Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use. Task Force of the European Society of Cardiology the North American Society of Pacing Electrophysiology. Circulation. 1996;93:10431065).

Time domain indexesSDNNStandard deviation of all NN intervals
SDANNStandard deviation of the averages of NN intervals in all 5-minute segments of the entire recording
RMSSDThe square root of the mean of the sum of the squares of differences between adjacent NN intervals
SDNN indexMean of the standard deviations of all NN intervals for all 5-minute segments of the entire recording
pNN50NN50 count divided by the total number of all NN intervals

Frequecy domain indexesTotal powerVariance of all NN intervals (≤0.4 Hz)
ULFPower in the ULF range (≤0.003 Hz)
VLFPower in the VLF range (0.003–0.04 Hz)
LFPower in the LF range (0.04–0.15 Hz)
HFPower in the HF range (0.15–0.4 Hz)
LF/HFRatio LF [ ]/HF[ ]