(Radio)Biological Optimization of External-Beam Radiotherapy
Figure 4
The variation of NTCP for radiation pneumonitis and oesophagitis, respectively, as a function of the number of fractions for a NSC lung radiotherapy case planned using tomotherapy (IMRT) and 3-D conformal techniques. The total dose is adjusted for tumour isoeffect using . The increase in oesophageal NTCP is consistent with the conventional application of the Withers formula [41], but the near constancy of lung NTCP is definitely not. Note also that the NTCP values are consistently lower for the more conformal tomotherapy plan (from [42]).
