Research Article

Recursive Feature Selection with Significant Variables of Support Vectors

Table 10

Selected biomarkers on the lung cancer dataset.

MarkerRankGene titleGene symbol -statistics value

D13705_s_at 1 Cytochrome P450, family 4, subfamily A, polypeptide 11CYP4A11 5.743 9.52E−04
HG1103-HT1103_at 2 −5.434 1.77E−03
X07618_s_at 5 Cytochrome P450, family 2, subfamily D, polypeptide 6CYP2D6 4.785 9.89E−03
Z71460_at 9 ATPase, H+ transporting, lysosomal V0 subunit a1ATP6V0A1 4.644 0.0124
AFFX-HUMGAPDH/M33197_M_at 10 Glyceraldehyde-3-phosphate dehydrogenaseGAPDH −4.496 0.0131
M37583_at 13 H2A histone family, member ZH2AFZ −4.445 0.0132
AFFX-HUMGAPDH/M33197_5_at 19 Glyceraldehyde-3-phosphate dehydrogenaseGAPDH −4.161 0.0153
AFFX-HUMRGE/M10098_3_at 20 4.098 0.0153
D13748_at 22 Eukaryotic translation initiation factor 4A, isoform 1EIF4A1 −4.245 0.0153
HG2279-HT2375_at 23 −4.099 0.0153
L14922_at 26 Replication factor C (activator 1) 1, 145 kDaRFC1 −4.138 0.0153
U37143_at 35 Cytochrome P450, family 2, subfamily J, polypeptide 2CYP2J2 4.245 0.0153
HG1153-HT1153_at 48 −4.031 0.0157
HG651-HT5209_s_at 49 3.995 0.0157
X01677_f_at 60 Glyceraldehyde-3-phosphate dehydrogenaseGAPDH −4.008 0.0157
U25433_at 65 CATR tumorigenicity conversion 1CATR1 3.971 0.0161
U38864_at 70 Zinc finger protein 212ZNF212 3.941 0.0166
X77584_at 100 ThioredoxinTXN −3.807 0.0186
AFFX-HUMGAPDH
/M33197_3_at
101 Glyceraldehyde-3-phosphate dehydrogenaseGAPDH −3.774 0.0191
L34060_at 103 Cadherin 8, type 2CDH8 3.789 0.0191
U96769_rna1_at 108 ChondroadherinCHAD 3.782 0.0191
HG2855-HT2995_at 122 −3.714 0.0205
U66617_at 128 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1SMARCD1 3.706 0.0205
U77970_at 191 Neuronal PAS domain protein 2NPAS2 3.544 0.0237
L25085_at 195 Sec61 beta subunitSEC61B −3.535 0.024
D45248_at 243 Proteasome (prosome, macropain) activator subunit 2 (PA28 beta)PSME2 −3.407 0.0285
U55764_at 273 Sulfotransferase family 1E, estrogen-preferring, member 1SULT1E1 3.359 0.0303
J03258_at 295 Vitamin D (1,25-dihydroxyvitamin D3) receptorVDR −3.314 0.0316
L19067_at 430 v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)RELA −3.106 0.0424
D38583_at 433 S100 calcium binding protein A11S100A11 −3.098 0.0431
HG2815-HT2931_at 475 −3.039 0.0469
U20350_at 610 Chemokine (C-X3-C motif) receptor 1CX3CR1 2.891 0.0567
U08815_at 772 Splicing factor 3a, subunit 3, 60 kDaSF3A3 2.743 0.0683

Rank: gene-ranking is computed using values.