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Computational and Mathematical Methods in Medicine
Volume 2012, Article ID 736320, 7 pages
Research Article

Automated Quantification of Pneumothorax in CT

1Department of Radiology, Massachusetts General Hospital, 25 New Chardon Street, Suite 400B, Boston, MA 02114, USA
2Albany Medical College, Albany, NY 12208, USA

Received 13 August 2012; Accepted 9 September 2012

Academic Editor: Gary C. An

Copyright © 2012 Synho Do et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An automated, computer-aided diagnosis (CAD) algorithm for the quantification of pneumothoraces from Multidetector Computed Tomography (MDCT) images has been developed. Algorithm performance was evaluated through comparison to manual segmentation by expert radiologists. A combination of two-dimensional and three-dimensional processing techniques was incorporated to reduce required processing time by two-thirds (as compared to similar techniques). Volumetric measurements on relative pneumothorax size were obtained and the overall performance of the automated method shows an average error of just below 1%.