How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

<table>The lower panel shows that <svg height="10.925" id="M92" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 17.3125 10.925" width="17.3125" xmlns="http://www.w3.org/2000/svg">
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</svg> is trivially independent of <svg height="12.8875" id="M93" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 11.1125 12.8875" width="11.1125" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑡</tspan>
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</svg> whereas the upper panel showing <svg height="10.925" id="M94" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 17.3125 10.925" width="17.3125" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑚</tspan>
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</svg> tells that, overall, there exists an optimal timing for the boost that is greater than 45 days. </table>

Computational and Mathematical Methods in Medicine

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Figure 5

Figure 5: How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System 