Computational and Mathematical Methods in Medicine / 2012 / Article / Tab 1

Research Article

How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

Table 1

Biological rules coding for interactions between cells or among cells and molecules and other specific mechanisms of the immune system. Each of the entries of this list corresponds to an algorithm implementing a specific activity of the immune cells.

Interactions Activations

B phagocytosis of antigen Activation of M πœ™
M πœ™ phagocytosis of antigen B cells anergy
DC phagocytosis of antigen TH cells anergy
B presentation to TH Priming of TH cells
M πœ™ presentation to TH TC cells anergy
DC presentation to TH Activation of TC cells
Formation of immunocomplexes (IC)  
M πœ™ phagocytosys  
Infection of EP cells  
Cytotoxicity of infected cells by TC  

Antigen ingestion and presentation Other procedures

B exogenous pathway Clone divisions
M πœ™ exogenous pathway Hematopoiesis
DC exogenous pathway Plasma secretion of immunoglobulins
EP endogenous pathway Entity movement
  Hypermutation of antibody

B: B cell, M πœ™ : macrophage, DC: dendritic cell, TC: cytotoxic CD8+ T cell, Th: CD4+ T cell.

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