Discrete-State Stochastic Models of Calcium-Regulated Calcium Influx and Subspace Dynamics Are Not Well-Approximated by ODEs That Neglect Concentration Fluctuations

<table>Calmodulin regulation of the calcium channel at steady-state. (A) State diagram of calmodulin regulation of a calcium channel (modified from [<a href="/journals/cmmm/2012/897371/#B31">31</a>]). (B) Steady-state probability distribution for the calmodulin-activated channel using (a) “slow CaM" and (b) “SQS" parameters [<a href="/journals/cmmm/2012/897371/#B31">31</a>]. </table>

Computational and Mathematical Methods in Medicine

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Figure 11

Figure 11: Discrete-State Stochastic Models of Calcium-Regulated Calcium Influx and Subspace Dynamics Are Not Well-Approximated by ODEs That Neglect Concentration Fluctuations 

Figure 11 | Discrete-State Stochastic Models of Calcium-Regulated Calcium Influx and Subspace Dynamics Are Not Well-Approximated by ODEs That Neglect Concentration Fluctuations 