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Computational and Mathematical Methods in Medicine
Volume 2013 (2013), Article ID 134163, 11 pages
Review Article

The Strength-Interval Curve in Cardiac Tissue

Department of Physics, Oakland University, Rochester, MI 48309, USA

Received 4 October 2012; Accepted 16 January 2013

Academic Editor: Socrates Dokos

Copyright © 2013 Sunil M. Kandel and Bradley J. Roth. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The bidomain model describes the electrical properties of cardiac tissue and is often used to simulate the response of the heart to an electric shock. The strength-interval curve summarizes how refractory tissue is excited. This paper analyzes calculations of the strength-interval curve when a stimulus is applied through a unipolar electrode. In particular, the bidomain model is used to clarify why the cathodal and anodal strength-interval curves are different, and what the mechanism of the “dip” in the anodal strength-interval curve is.