Research Article

Superficial Collagen Fibril Modulus and Pericellular Fixed Charge Density Modulate Chondrocyte Volumetric Behaviour in Early Osteoarthritis

Figure 2

Microscopic analyses of the anterior cruciate ligament transected (ACLT) and contralateral (CNTRL) cartilage sections as a function of the normalized tissue depth (0 = surface, 1 = cartilage-bone interface) [22]. (a) Depth-dependent optical density (OD) representing proteoglycan content of the ACLT and CNTRL cartilage. (b) Depth-dependent collagen fibril orientation angle of the ACLT and CNTRL cartilage. Data is presented as mean ± S.D. between the groups.
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(a)
164146.fig.002b
(b)