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Computational and Mathematical Methods in Medicine
Volume 2013, Article ID 283593, 13 pages
http://dx.doi.org/10.1155/2013/283593
Research Article

Spatiotemporal Dynamic Simulation of Acute Perfusion/Diffusion Ischemic Stroke Lesions Evolution: A Pilot Study Derived from Longitudinal MR Patient Data

1Division of Neuroimaging Sciences, Brain Research Imaging Centre (BRIC), Edinburgh University, UK
2CMAP, Ecole Polytechnique, route de Saclay, 91128 Palaiseau, France
3INRIA, ICM Pitié-Salpétrière Hospital, Paris, France

Received 21 December 2012; Revised 22 May 2013; Accepted 22 May 2013

Academic Editor: Edelmira Valero

Copyright © 2013 Islem Rekik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

These videos show the diffusion and perfusion lesions as they deform in space and time and visualize the different expanding areas in both lesions. Video 1 displays the estimated spatiotemporal evolution scenario of MTT lesion (in red) and DWI lesion (in blue) from acute to subacute timepoints (video 1). Videos 2 and 3 are dynamic translations of Figure 5 (see manuscript): in video 2 you can see the “lighting up” process of successively highly expanding DWI regions along the evolution process, all visualized on the baseline surface at the first acquisition timepoint t1; and in video 3 you can see consecutively highly expanding MTT regions “lighting up” from acute to subacute stages, all mapped back into the baseline MTT lesion surface acquired at timepoint t1.

  1. Supplementary Videos