Research Article

Evaluation of a Model-Based Hemodynamic Monitoring Method in a Porcine Study of Septic Shock

Table 1

List of identified parameters and corresponding measurements used to identify them for the simplified systemic, simplified pulmonary, and six-chamber models. Each line on the table represents a measurement/parameter pair, where the measurement on the line is used to directly identify the corresponding parameter. All the parameters in this table, except for the valve resistances, are uniquely identified for each set of measurements. The valve resistances are identified for each set of measurements and then averaged for a subject.

ModelMeasurement Identified parameter
NameSymbolNameSymbol

SystemicGlobal end diastolic volumeGEDVLeft ventricular elastance
Stroke volumeSVMitral valve resistance
Mean aortic pressureMAPSystemic vascular resistance
Aortic pulse pressure Aortic elastance
Maximum ascending aortic gradient Aortic valve resistance
Mitral valve closure time Pulmonary vein pressure

PulmonaryGlobal end diastolic volumeGEDVRight ventricular elastance
Stroke volumeSVTricuspid valve resistance
Mean pulmonary artery pressureMPAPPulmonary valve resistance
Pulmonary artery pulse pressure Pulmonary artery elastance
Maximum ascending pulmonary artery pressure Pulmonary valve resistance
Tricuspid valve closure time Vena cava pressure

6 chamberVena cava pressure (identified from systemic model) Vena cava elastance
Pulmonary vein pressure (identified from pulmonary model) Pulmonary vein elastance