Influence of Distal Resistance and Proximal Stiffness on Hemodynamics and RV Afterload in Progression and Treatments of Pulmonary Hypertension: A Computational Study with Validation Using Animal Models

Table 2

Four stages from control to hypertensive conditions during PAH progression (each stage one parameter increased from previous stage).

Control	All parameters from control state (Table 1)
Hyper PVR	PVR: 4.91 → 15.1 mm Hg/(L/min)
Hyper EM	EM: 97.1 → 177 kPa
Hyper h	h: 3.38 → 3.95 mm