crcTRP: A Translational Research Platform for Colorectal Cancer

Table 1

Representative clinic-genomic relations about colorectal cancer.

Clinical data items	Genes
Abdominal pain	FOS, HFE, NRAS, TP53
Blood glucose	BAX, CCND1, CTNNB1, FGFR3, FOS, PPARG, SRG, TLR2, TP53
Carcinoembryonic antigen	APC, BAX, CCND1, CEACAM5, CEACAM7, CEACAM1, CTNNB1, DCC, EGFR, ERBB2, MLH1, MSH2, PSG2, SRC, TLR2, TP53
CA19-9 antigen	CTNNB1, NRAS, TP53, SRC
Colorectal neoplasms staging	APC, CCND1, CTNNB1, MTHFR, PPARG, TP53
Crohn’s disease	APC, BAX, CCND1, CTNNB1, DCC, MTHFR, NRAS, PPARG, TLR2, TP53
Diabetes mellitus	APC, BAX, CCND1, CHEK2, CTNNB1, DCC, FGFR3, MTHFR, NRAS, PPARG, PTPN12, SRC, TLR2, TP53
Dyspepsia	PPARG
Intestinal obstruction	APC, CCND1, MSH2, PPARG, TLR2
Lymphatic metastases	MCC, TP53, APC, BAX, CCND1, CTNNB1