Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking

Table 4

Epitope mapping solution no. 2 based on mimotope analysis.

Mimotope	Predicted epitopic residues
YPHFHKHTLRGH	T28, K36, L38, K57, F74, G83, L101, H102, G103, P104, P132, K191
YPHFHKHSLRGQ	K36, L38, K57, F74, S78, Q81, G83, S86, Q100, L101, H102, G103, P104, P132, K191
DHKPFKPTHRTL	T28, K36, L38, K57, F74, D77, D79, D80, L101, H102, P104, P132, K191
FHKPFKPTHRTL	T28, K36, L38, K57, F74, L101, H102, P104, P132, K191
QSSCHKHSVRGR	V30, K36, K57, S78, Q81, G83, S86, Q100, H102, G103, V131, K191
QSSFSNHSVRRR	V30, F74, S78, Q81, S86, N98, Q100, H102, V131
Union	T28, V30, K36, L38, K57, F74, D77, S78, D79, D80, Q81, G83, S86, N98, Q100, L101, H102, G103, P104, V131, P132, K191; 22 residues in total.