Understanding the Pathogenesis of Kawasaki Disease by Network and Pathway Analysis

Table 2

Susceptibility genes for KD identified with association at genome-wide significance.

Gene	Locus	Methods	Reference
FCGR2A	1q23	GWAS	[91]
BLK	8p23-p22	GWAS	[92, 93]
CASP3	4q34	Genome wide Linkage analysis	[94]
ITPKC	19q13.1	Genome wide Linkage analysis; linkage disequilibrium mapping	[94, 95]
CD40L	Xq26	Genome wide Linkage analysis	[94]
CD40	20q12-q13.2	GWAS	[92, 93]
HLA-DQB2	6p21	GWAS	[92]
HLA-DOB	6p21.3	GWAS	[92]
NFKBIL1	6p21.3	GWAS	[92]
LTA	6p21.3	GWAS	[92]
NAALADL2	3q26.31	GWAS	[96]
ZFHX3	16q22.3	GWAS	[96]
DAB1	1p32-p31	GWAS	[97]
PELI1	2p13.3	GWAS	[97]
COPB2	3q23	GWAS	[98]
ERAP1	5q15	GWAS	[98]
IGHV	14q32.33	GWAS	[98]
ABCC4	13q32	Genome-wide linkage and association mapping	[99]

GWAS: genome-wide association study.