Human Atrial Cell Models to Analyse Haemodialysis-Related Effects on Cardiac Electrophysiology: Work in Progress

Table 3

Qualitative summary of HD-induced [Ca²⁺ variation on selected AP biomarkers. Results are shown for a Ca²⁺ increase, butdepending on the [Ca²⁺] concentration in the dialysis bath, a decrease could occur as well.

[Ca^2+; ↗	APD	ERP	CaTamp	[Ca^2+	[Na^+
			↗	↗	?
	[30, 64–66]		[66]	[66]
CN	−	−−	++	++	−
NG	−−	−−	++	++	=
MT	−−	−−	++	++	=
KT^*	−	−−	+	++	=
GB	++, *	++, *	++	++	+
CZ	−−	−−	=, *	++	−

APD: AP duration; ERP: effective refractory period; CaTamp: Ca²⁺-transient amplitude; black arrows: expected increase/decrease during HD, with the corresponding references, +/++/−/−−: moderate/large biomarker increase/decrease; *: biomarker changes different from the expected ones.