Computational Modeling of Interventions and Protective Thresholds to Prevent Disease Transmission in Deploying Populations

Table 5

Model parameters for hepatitis B transmission model.

Parameter	Description	Value	Source
𝑏IN	Inward troop rotation rate		[3, 16]
𝑏OUT	Outward troop rotation rate		[3, 16]
𝛽𝑖𝑖	Effective transmission rate within unit 𝑖	Function of attack rate
𝛽𝑖𝑗	Effective transmission rate between units 𝑖 and 𝑗	Function of attack and contact rates
𝛽𝑖LOCAL	Effective transmission rate between unit 𝑖 and local population	Function of attack rate, contact rate, and local HBV prevalence
𝑐𝑖	Contact rate with local population for unit 𝑖	Varies by unit
𝐶𝑖𝑗	Contact rate between unit 𝑖 and unit 𝑗	Varies by unit
𝜒	HBV attack rate (for soldiers)	25% (11%–71%)	[68–71]
incLOCAL	HBV prevalence rate for local population	5%	[18, 66, 67]
1/𝜀	Duration of HBV incubation period	90 days (60–90 days)	[57]
1/𝛾𝐴	Duration of HBV acute infection period	28 days (23–28 days)	[72]
1/𝛾𝑐	Duration of HBV chronic infection period	40 years (lifelong)	Calibrated
𝜓	Conversion rate from acute to chronic HBV infection	5% (2%–90%)	[65]
𝜇	Casualty rate for all units (nondisease related)	0.0007825	[16]
𝜇𝐴	Acute infection mortality rate for all units	1% (0.2%–1%)	[57]
𝜌1, 𝜌2, 𝜌3	Vaccination rate for doses 1, 2, and 3 (96% vaccine efficacy)	Scenario-dependent
1/𝜎1	Duration of 𝑉1 status prior to second dose vaccination	28 days	[57]
1/𝜎2	Duration of 𝑉2 status prior to third dose vaccination	150 days	[57]