First Comprehensive <i>In Silico</i> Analysis of the Functional and Structural Consequences of SNPs in Human <i>GalNAc-T1</i> Gene

<table>Multiple sequence alignments and evolutionary conservation behaviour among human <i>GalNAc-T1</i> to <i>GalNAc-T10</i> members of GALNTs family. S143 and Y414 residues are found conserved in the catalytic subdomain A and linker B domain (area between catalytic subdomain B and Ricin B-type lectin), respectively. G258 is observed in the vicinity of conservation groups with strongly similar properties (shown with “:”).</table>

Computational and Mathematical Methods in Medicine

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Figure 4

Figure 4: First Comprehensive <i>In Silico</i> Analysis of the Functional and Structural Consequences of SNPs in Human <i>GalNAc-T1</i> Gene 

Computational and Mathematical Methods in Medicine

First Comprehensive In Silico Analysis of the Functional and Structural Consequences of SNPs in Human GalNAc-T1 Gene

Figure 4