Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with Diseases

Table 2

Numbers and values of exact matched nsSNVs related to inherited diseases and cancers on each PTM type.

PTM	Inherited disease	value	Cancer	value
Phosphorylation	313	0.0133	2684	0.0197
Ubiquitylation	59	0.0807	651	0.0172
Acetylation	34	0.0701	233	0.1058
Glycosylation	13	0.2062	57	0.1813
Methylation	15	0.1638	67	0.0912
SUMOylation	1	0.7752	22	0.0152
Hydroxylation	2	0.7423	14	0.3507
Sulfation	4	0.5503	0	0.5503

values in this column were calculated using hypergeometric test and all values refer to the left column (genetic disease).