Genetic Consequences of Antiviral Therapy on HIV-1

Figure 1

Overall sequence diversity variation and Kullback-Leibler divergence. (a) Variation of overall sequence difference between the two datasets of each evolutionary scenario ( − ). Indels are considered as missing data. Error bars indicate standard error. Reference values are shown in Table S1 (Supplementary Material). (b): Kullback-Leibler distance, nucleotide diversity distribution, between the two datasets of each evolutionary scenario. Dark grey bars consider indels as a new state whereas clear grey bars consider indels as missing data. Error bars indicate standard error across sites. “−” indicates naïve-treatment patients.

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