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Computational and Mathematical Methods in Medicine
Volume 2015, Article ID 512929, 7 pages
http://dx.doi.org/10.1155/2015/512929
Research Article

Donor/Recipient Delta Age: A Possible Risk for Arterial Stenosis in Renal Transplantation

1Faculty of Medicine and Surgery, Department of Physics, University of Bologna, Via Berti Pichat 6/2, 40127 Bologna, Italy
2Nephrology Dialysis and Renal Transplantation Unit, S. Orsola University Hospital, Via Massarenti 9, 40138 Bologna, Italy
3Department of Statistical Sciences, University of Bologna, Via Belle Arti 41, 40126 Bologna, Italy
4Service of Biostatistics, Niguarda Cà Granda Hospital, Piazza Ospedale Maggiore 3, 20162 Milan, Italy

Received 17 September 2015; Revised 24 November 2015; Accepted 15 December 2015

Academic Editor: Reinoud Maex

Copyright © 2015 Giovanni Pallotti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Different arterial wall properties can significantly increase the risk of blood turbulent fluxes leading to complications such as atherosclerosis. Since the mechanical properties of arterial vessels are influenced by age, we investigated, in a retrospective study, the effects on renal artery stenosis of an age difference >15 years between donor and recipient in a cohort of 164 patients undergoing renal transplantation between 1981 and 1991. The age difference between donor and recipient was ≤15 years in 87 patients (53.0%) (Group A) and >15 years in 77 patients (47.0%) (Group B, ). None of the Group A patients developed an anastomotic arterial stenosis, whereas 8/77 Group B patients (10.4%) had an anastomotic arterial stenosis (). This study shows that an age difference >15 years is significantly linked to the risk of developing arterial stenosis after renal transplantation. Indeed, different wall properties can significantly increase the risk of generation of blood turbulent fluxes and involve, in the arterial vessels, the development of complications such as atherosclerosis.