Unified Modeling of Familial Mediterranean Fever and Cryopyrin Associated Periodic Syndromes

Table 2

The parameters used in the model.

	Explanation
	Maximum rate of I and A binding to the receptor
	Strength of positive feedback
	Strength of negative feedback
	Maximum rate to form Cryopyrin inflammasome
	Maximum rate of PC production
	Threshold for I to induce R
	Threshold for A to suppress R
	Threshold for R to induce I
	Threshold for R to induce A
	Threshold for PC to induce C
	Threshold for T to induce C
	Threshold for P to suppress C
	Threshold for P to suppress PC
	Degradation rate of R
	Degradation rate of I
	Degradation rate of A
	Degradation rate of C
	Degradation rate of PC
	Basal synthesis rate of R
	Basal synthesis rate of A
	Basal synthesis rate of C
	Basal synthesis rate of PC
	Conversion rate of PC into C
	Hill function cooperativity exponent
	Proportionality constant of C and I