Research Article

Modeling the Interaction between β-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model

Table 1

Dimensionless forms of the ordinary differential equations of ChAT inhibition effects by β-amyloid aggregates of kinetic mechanism 1.

ItemCompartmentDifferential equation

Hydrogen protons1
2

Acetylcholine (ACh) 1
2

Choline1
2

Acetate1
2

-amyloid aggregates (A)1

Rate of synthesis ()1

Rate of hydrolysis ()2