Computational and Mathematical Methods in Medicine

Research Article

A Canonical Correlation Analysis of AIDS Restriction Genes and Metabolic Pathways Identifies Purine Metabolism as a Key Cooperator

Table 4

Cross-correlation of genes enriched in metabolic pathways with canonical variate.
ComponentTermCountPop hits valueGenes
+Purine metabolism31535143, 51728, 5558
3+Glycolysis/gluconeogenesis3605223, 2597, 57818
3+Pyrimidine metabolism3955425, 51727, 7372
4−Purine metabolism41531716, 51728, 55703, 5313
4+Purine metabolism515355811, 5147, 5425, 5432, 8654
5−Inositol phosphate metabolism3548871, 5330, 3707
6−Pyrimidine metabolism3955435, 51727, 84172
6+Pyruvate metabolism3405162, 4191, 38
6+Terpenoid backbone biosynthesis2152224, 38
7−Pyrimidine metabolism39554963, 5435, 5430
7+Methane metabolism26128, 4524