Research Article

Anesthetic Propofol-Induced Gene Expression Changes in Patients Undergoing Coronary Artery Bypass Graft Surgery Based on Dynamical Differential Coexpression Network Analysis

Table 4

Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of genes in key modules based on false discovery rate (FDR) < 0.01 and gene count ≥ 10.

ModulesKEGG pathwaysGene countFDR

Module 1 Neuroactive ligand-receptor interaction15
Module 2 Neuroactive ligand-receptor interaction37
Module 3 Neuroactive ligand-receptor interaction10
Module 4Cytokine-cytokine receptor interaction29
JAK-STAT signaling pathway20
Toll-like receptor signaling pathway11
Natural killer cell mediated cytotoxicity12
Module 5 Neuroactive ligand-receptor interaction10
Module 6 Neuroactive ligand-receptor interaction33
Module 7 Neuroactive ligand-receptor interaction16
Module 8Steroid hormone biosynthesis11