Towards the Design of a Patient-Specific Virtual Tumour

Figure 5

Comparison of the growth evolution of a simulated tumour (tumour case M4-L) with its real counterpart at four time points (days 3, 7, 14, and 28). (a) Bright field images of the tumour with 2x objective and RFP-fluorescence image of the vasculature (on day 14); (b) associated virtual tumour exhibiting the tumour cells (proliferative cells in light grey and quiescent cells in grey), vessels (darker vessels are larger), and VEGF distribution (in red); (c) oxygen level (dark spots for oxygen levels lower than normal and bright spots for oxygen levels higher than normal). Scale bars: 1 mm for experimental images (a); 500  for simulated images (b, c).

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