Computational and Mathematical Methods in Medicine / 2016 / Article / Fig 7

Research Article

In Silico Evaluation of the Potential Antiarrhythmic Effect of Epigallocatechin-3-Gallate on Cardiac Channelopathies

Figure 7

Effects of p.R222Q and p.I141V mutations on properties in the human Purkinje cell model (SANNBZ cell model). (a) and (b) Effect of the p.R222Q mutation on the voltage dependence of steady state of activation and inactivation. (c) and (d) Effect of the p.R222Q mutation on the activation and inactivation kinetics. (e) and (f) Effect of the p.I141V mutation on the voltage dependence of steady state of activation and inactivation. (g) and (h) Effect of the p.I141V mutation on the activation and inactivation kinetics. For all panels, black lines: WT condition; red lines: mutant conditions.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)

We are experiencing issues with article search and journal table of contents. We are working on a fix as to remediate it and apologise for the inconvenience.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.