Establishment of Relational Model of Congenital Heart Disease Markers and GO Functional Analysis of the Association between Its Serum Markers and Susceptibility Genes

Table 7

The same GO semantic annotation of NKX2.5 gene and serum markers Lp(a) and BNP.

Gene	GO number	Annotation	Ontology	Evidence	Reference	Serum marker
NKX2.5	0010467	Gene expression	Biological process	TAS	Reactome: REACT_71	Brain natriuretic peptide (BNP)
	0006367	Transcription initiation from RNA polymerase II promoter	Biological process	TAS	Reactome: REACT_118713; Reactome: REACT_12627
	0007166	Cell surface receptor signaling pathway	Biological process	NAS	PMID: 12727915
	0008015	Blood circulation	Biological process	TAS	PMID: 8047165	Lipoprotein(a); (Lp(a))
	0055085	Transmembrane transport	Biological process	TAS	Reactome: REACT_15480
	0007399	Nervous system development	Biological process	IEA: with Ensemb ENSMUSP00000036044	GO REF: 0000019