Computational and Mathematical Methods in Medicine / 2017 / Article / Tab 9

Research Article

Defining an Optimal Cut-Point Value in ROC Analysis: An Alternative Approach

Table 9

The true cut-point estimates obtained by all the methods: some of cut-points and the AUC values for pulse pressure, LVEF, plasma sodium level and heart rate in prediction of mortality.

Pulse pressureLVEFPlasma sodiumHeart rate
Point (Se, Sp)Point (Se, Sp)Point (Se, Sp)Point (Se, Sp)

Youden index30 (83.7, 79.7)0.264 (62.8, 84.7)137 (93.0, 48.3)99 (32.6, 91.5)
ER30 (83.7, 79.7)0.295 (76.7, 69.5)135 (72.1, 66.9)85 (62.8, 58.5)
Min value24 (98.3, 53.5)0.235 (46.5, 94.9)130 (39.5, 92.4)115 (16.3, 99.2)
CZ30 (83.7, 79.7)0.295 (76.7, 69.5)135 (72.1, 66.9)85 (62.8, 58.5)


Some cut-off points with their sensitivity and specificity values

24 (53.5, 98.3)
27 (81.4, 79.7)
30 (83.7, 79.7)
34 (83.7, 77.1)
37 (100, 39.0)

0.272 (65.1, 81.4)
0.282 (67.4, 76.3)
0.290 (69.8, 75.4)
0.295 (76.7, 69.5)
0.303 (81.4, 61.0)

133 (53.5, 82.2)
134 (60.5, 76.3)
135 (72.1, 66.9)
136 (81.4, 57.6)
137 (93.0, 48.3)

84 (67.4, 53.4)
85 (62.8, 58.5)
86 (58.1, 61.9)
87 (51.2, 68.6)

Index of Union30 (83.7, 79.7)0.295 (76.7, 69.5)135 (72.1, 66.9)85 (62.8, 58.5)

AUC0.8920.8090.7770.647

Note. Point: cut-point; Se: sensitivity; Sp: specificity; AUC: the area under the curve.

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