Computational and Mathematical Methods in Medicine / 2017 / Article / Tab 2

Research Article

Dendritic Immunotherapy Improvement for an Optimal Control Murine Model

Table 2

Model parameters.

ParameterDescriptionValuesUnits h = hours, c = cellReference

Birth rate of CD4 T[10]
Death rate of CD4 T[10]
Max proliferation of CD4 T1[10]
Carrying capacity of CD4 T1[10]
Birth rate of CD8 T[10]
Death rate of CD8 T[10]
Max proliferation of CD8 T[10]
Carrying capacity of CD8T[10]
Tumor growth rateAd hoc value
Maximum efficiency of cytotoxic cellsAd hoc value
DC arriving time delay at lymph nodesAd hoc value
Tumor carrying capacity[6]
Rate death of DCs[7]
IL-2 production by CD4 T[10]
IL-2 uptake by CD8 T[10]
IL-2 degradation rate[10]
Michaelis constant[6]
Michaelis constantnone[6]
Michaelis constant[6]
Production rate of TGF-β[6]
Degradation rate of TGF-β[6]
Release rate per single CTL[6]
Degradation of [6]
Receptor production[6]
Maximal effect of IFN-c[6]
Michaelis parameter[6]
Degradation of MI[6]
Active DC percentage[8]

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