Dendritic Immunotherapy Improvement for an Optimal Control Murine Model

Table 2

Model parameters.

Parameter	Description	Values	Units h = hours, c = cell	Reference
	Birth rate of CD4 T			[10]
	Death rate of CD4 T			[10]
	Max proliferation of CD4 T	1		[10]
	Carrying capacity of CD4 T	1		[10]
	Birth rate of CD8 T			[10]
	Death rate of CD8 T			[10]
	Max proliferation of CD8 T			[10]
	Carrying capacity of CD8T			[10]
	Tumor growth rate			Ad hoc value
	Maximum efficiency of cytotoxic cells			Ad hoc value
	DC arriving time delay at lymph nodes			Ad hoc value
	Tumor carrying capacity			[6]
	Rate death of DCs			[7]
	IL-2 production by CD4 T			[10]
	IL-2 uptake by CD8 T			[10]
	IL-2 degradation rate			[10]
	Michaelis constant			[6]
	Michaelis constant		none	[6]
	Michaelis constant			[6]
	Production rate of TGF-β			[6]
	Degradation rate of TGF-β			[6]
	Release rate per single CTL			[6]
	Degradation of			[6]
	Receptor production			[6]
	Maximal effect of IFN-c			[6]
	Michaelis parameter			[6]
	Degradation of MI			[6]
	Active DC percentage			[8]