Research Article

Node-Structured Integrative Gaussian Graphical Model Guided by Pathway Information

Algorithm 1

The structured alternating directions method of multipliers algorithm.
(1) Initialize , and for .
(2) Update , and until convergence for :
 (i) -step
 Update that minimizes
 (ii) -step
 For , update that minimizes
,
 where .
 (iii) -step
 For , update as .
(3) Output .