Computing Individual Risks Based on Family History in Genetic Disease in the Presence of Competing Risks

Figure 1

A hypothetical family with a severe FH of cancer. Squares correspond to males, circles correspond to females, and affected individual are filled in black. Individual id on the top-right of the nodes, personal history of cancer (UN = unaffected; BC = breast cancer; OC = ovarian cancer) on the bottom-right. The dashed line represents an identity link used to represent the mating loop (due to the mating between individuals 5/8 and 6/7) between brothers 5 and 6 and sisters 7 and 8.