The Application of Dynamic Models to the Exploration of -AR Overactivation as a Cause of Heart Failure

Figure 5

The block diagram of interaction model. We also take -AR () into consideration in the reaction based on medical experiments. According to the studies of laboratory animal medicine of Capital Medical University, they found that -AA had a unique characteristic that can inhibit heterodimerization of -AR and thus lead to decompose of -AR and -AR that are originally connected, resulting in endocytosis inhibition and sustained activation of the signal. Therefore, there is no conjugation of -AR and -AR () in the products. Besides, -AA (I) cannot directly bind to -AR (), so there is no in the products. Thus, we consider that (I and are combined to ) are intermediate complexes and , are the products with structure change.