Research Article
Maximin Efficiencies under Treatment-Dependent Costs and Outcome Variances for Parallel, AA/BB, and AB/BA Designs
| Treatment by period interaction | | N | Crossover design | Extended parallel design |
| Type I error rate = 0.05 | | | | | | [0.01, 0.10] | [0.01, 0.10] | 110 | 0.799 (0.90) | 0.840 (1) | [0.01, 0.30] | [0.01, 0.30] | 130 | 0.801 (0.76) | 0.899 (1) | [0.70, 1.00] | [0.70, 1.00] | 34 | 0.206 (0.15) | 0.830 (1) | [0.90, 1.00] | [0.90, 1.00] | 15 | 0.111 (0.05) | 0.883 (1) |
| Type I error rate = 0.01 | | | | | | [0.01, 0.10] | [0.01, 0.10] | 166 | 0.808 (0.90) | 0.848 (1) | [0.01, 0.30] | [0.01, 0.30] | 194 | 0.800 (0.76) | 0.912 (1) | [0.70, 1.00] | [0.70, 1.00] | 51 | 0.117 (0.15) | 0.840 (1) | [0.90, 1.00] | [0.90, 1.00] | 23 | 0.048 (0.05) | 0.911 (1) |
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Note. The power printed in bold indicates the design for which the sample calculation should yield a power of 80%. N: total sample size.
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