TY - JOUR A2 - Nishizawa, Kazuhisa AU - Kpekpena, Cynthia AU - Muthukumarana, Saman PY - 2018 DA - 2018/08/08 TI - Bayesian Equivalence Testing and Meta-Analysis in Two-Arm Trials with Binary Data SP - 8134132 VL - 2018 AB - We consider a Bayesian approach for assessing hypotheses of equivalence in two-arm trials with binary Data. We discuss the development of likelihood, the prior, and the posterior distributions of parameters of interest. We then examine the suitability of a normal approximation to the posterior distribution obtained via a Taylor series expansion. The Bayesian inference is carried out using Markov Chain Monte Carlo (MCMC) methods. We illustrate the methods using actual data arising from two-arm clinical trials on preventing mortality after myocardial infarction. SN - 1748-670X UR - https://doi.org/10.1155/2018/8134132 DO - 10.1155/2018/8134132 JF - Computational and Mathematical Methods in Medicine PB - Hindawi KW - ER -