Research Article

Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections

Figure 5

VEPART output at the experimental dose of Ad/4-1BBL/IL-12 and DCs used in Huang et al. [4]. The x axis indicates each of the 20 treatment protocols tested, with “V” representing Ad/4-1BBL/IL-12 treatment and “D” representing DC treatment on a given day. For each of the 20 treatment protocols, we see the frequency at which it ranks in positions 1 (best protocol) to 20 (worst protocol) for (a) the original model in system (1)–(6) and (b) the minimal model in system (11)–(15).
(a)
(b)