Comparing Strategies to Prevent Stroke and Ischemic Heart Disease in the Tunisian Population: Markov Modeling Approach Using a Comprehensive Sensitivity Analysis Algorithm

Algorithm 1

Comprehensive algorithm of the Markov model and of sensitivity analysis.

	Step I. Calculate probabilistic transition probabilities
	for all do
	for all age groups do
	for do
	end for
	end for
	end for
	Step II. Calculate the number of people in each state NHP, NS, and ND (Baseline scenario)
	for all do
	for all age groups do
	for do
	end for
	end for
	end for
	Step III. Calculate the number of people in each state for the interventions scenarios
	for all do
	for all age groups do
	for all intervention do
	where is the intervention risk reduction value and its age effects
	for
	end for
	end for
	end for
	end for
	Step IV. Calculate the final outputs (DPPs and LY)
	for all do
	for all age groups do
	for all intervention do
	end for
	end for
	end for
	end for
	Step V. Linear regression metamodeling
	Calculate the coefficients of the parameters
	for all do
	for all age groups do
	Solve the equation
	end for
	end for