Research Article
Evaluating the Cost-Effective Use of Follow-Up Colonoscopy Based on Screening Findings and Age
Table 7
Intercolonoscopy intervals for sensitivity analyses.
| Screen age | Outcome | Colonoscopy cost | Cancer cost | Discount rate | Low ($303) | High ($2,627) | Low | High |
| $100,000/QALYs gained |
| 50 years | Recommended follow-up interval | 8.5 years | n/c | 8.3 | 8.5 | 3.9, 4.0, 4.9, 6 years (437.22) | Range of cost-effective follow-up colonoscopy | 2–20 years | 10–20 years | 8–20 years | Gain in QALYs/10,000 persons | 84.0 | 83.9 | 84.0 | 55 years | Recommended follow-up interval | 6.8 | n/c | n/c | 5.8 | 3.6, 4.5, 5.8 years (305.52) | Range of cost-effective follow-up colonoscopy | 2–20 years | 10–14 years | Gain in QALYs/10,000 persons | 75.1 | 75.6 | 60 years | Recommended follow-up interval | 5.6 years | n/c | n/c | n/c | 6.4 years (120.01) | Range of cost-effective follow-up colonoscopy | 2–20 years | Gain in QALYs/10,000 persons | 62.6 | 65 years | Recommended follow-up interval | 4.3 years | n/c | n/c | n/c | n/a | Range of cost-effective follow-up colonoscopy | 2–14 years | Gain in QALYs/10,000 persons | 47.6 |
| $75,000/QALYs gained | 50 years | | n/c | n/c | n/c | n/c | 6.4, 8.1 years (307.30) | 55 years | | n/c | n/c | n/c | n/c | 8.2 years (157.14) |
| $50,000/QALYs gained | 50 years | | n/c | n/c | n/c | n/c | 10.3 years (194.12) |
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n/c scenarios that were not cost-effective |