Research Article

Evaluating the Cost-Effective Use of Follow-Up Colonoscopy Based on Screening Findings and Age

Table 7

Intercolonoscopy intervals for sensitivity analyses.

Screen ageOutcomeColonoscopy costCancer costDiscount rate
Low ($303)High ($2,627)LowHigh

$100,000/QALYs gained

50 yearsRecommended follow-up interval8.5 yearsn/c8.38.53.9, 4.0, 4.9, 6 years (437.22)
Range of cost-effective follow-up colonoscopy2–20 years10–20 years8–20 years
Gain in QALYs/10,000 persons84.083.984.0
55 yearsRecommended follow-up interval6.8n/cn/c5.83.6, 4.5, 5.8 years (305.52)
Range of cost-effective follow-up colonoscopy2–20 years10–14 years
Gain in QALYs/10,000 persons75.175.6
60 yearsRecommended follow-up interval5.6 yearsn/cn/cn/c6.4 years (120.01)
Range of cost-effective follow-up colonoscopy2–20 years
Gain in QALYs/10,000 persons62.6
65 yearsRecommended follow-up interval4.3 yearsn/cn/cn/cn/a
Range of cost-effective follow-up colonoscopy2–14 years
Gain in QALYs/10,000 persons47.6

$75,000/QALYs gained
50 yearsn/cn/cn/cn/c6.4, 8.1 years (307.30)
55 yearsn/cn/cn/cn/c8.2 years (157.14)

$50,000/QALYs gained
50 yearsn/cn/cn/cn/c10.3 years (194.12)

n/c scenarios that were not cost-effective