Improved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG

Figure 4

The longitudinal estimates from linear mixed effects models with and without considering the H5 strain subtype variations. The mean of longitudinal log concentration showed a total of 21 strains of H5 anti-HA IgG for each of the three different vaccine treatment groups (UPR, PR, and MPR), with and without strain subtype variation taken into account estimated from the linear mixed effects models with adjustment for the differences in dosages, batches, gender, ethnicity, and time points using the restricted maximum likelihood methods.