Research Article
Improved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG
Table 1
The mPlex-Flu assay panel of seasonal influenza viruses, H5 clades, and subclades.
| | Influenza virus type | Subtypes | Full name of viruses | Abbreviation | H5 clades/subclades |
| | A | H1 | A/South Carolina/1/18 | A/SC18 | | | A/Puerto Rico/8/1934 | A/PR8 | | | A/USSR/90/1977 | A/USSR77 | | | A/New Caledonia/20/1999 | A/NewCall99 | | | A/Texas/36/1991 | A/Tex91 | | | A/California/07/2009 | A/Cali09 | | | H2 | A/Japan/305/1957 | A/Jap57 | | | H3 | A/Port Chalmers/1/1973 | A/PC73 | | | A/Hong Kong/1/1968 | A/HK68 | | | A/Perth/16/2009 | A/Per09 | | | A/Victoria/361/2011 | A/Vic11 | | | A/Texas/50/2012 | A/Tex12 | | | H5 | A/Hong Kong/156/97 | A/HK97 | 0 | | A/Viet Nam/1203/2004 | A/Viet04 | 1 | | A/Cambodia/P0322095/2005 | A/Cam05 | 1.1 | | A/Indonesia/5/05 | A/Ind05 | 2.1.3.2 | | A/Turkey/65596/2006 | A/TK06 | 2.2.1 | | A/Common Magpie/Hong Kong/5052/2007 | A/cmHK07 | 2.3.2.1 | | A/Shenzhen/406H/2006 | A/SZ06 | 2.3.4 | | A/Chicken/Guangxi/12/2004 | A/chiGX04 | 2.4 | | A/Chicken/Korea/es/2003 | A/chiKR03 | 2.5 | | A/Silky Chicken/Hong Kong/SF189/01 | A/s.chiHK01 | 3 | | A/Goose/Guiyang/337/2006 | A/gooGY06 | 4 | | A/Duck/Guangxi/1378/2004 | A/ducGX04 | 5 | | A/Duck/Hubei/wg/2002 | A/ducHB02 | 6 | | A/Beijing/01/2003 | A/BJ03 | 7.1 | | A/Chicken/Shanxi/2/2006 | A/chiSX06 | 7.2 | | A/Chicken/Henan/16/2004 | A/chiHN04 | 8 | | A/Goose/Shantou/1621/05 | A/gooST05 | 9 | | A/duck/Sichuan/NCXN10/2014(H5N1) | A/ducSC14 | 2.3.4.4 | | A/turkey/Washington/61–22/2014(H5N2) | A/turWash14 | 2.3.4.4 | | A/duck/Guangdong/wy11/2008(H5N5) | A/ducGD08 | 2.3.4.4 | | A/turkey/California/K1500169-1.2/2015(H5N8) | A/turCal15 | 2.3.4.4 | | H6 | A/chicken/Taiwan/67/2013 | A/chTW13 | | | H7 | A/mallard/Netherlands/12/2000 | A/malNert00 | | | A/rhea/North Carolina/39482/1993 | A/rheaNC93 | | | H9 | A/guinea fowl/Hong Kong/WF10/1999 | A/gfHK99 | |
| | B | | B/Brisbane/60/2008 | B/Bris08 | |
| | HA domains | | Head of A/Shanghai/1/2013 | H7 Head | | | Head of A/Indonesia/5/05 | H5 Head | | | Headof A/guinea fowl/Hong Kong/WF10/1999 | H9 head | |
| | Chimeric HA | | cH5/1 (head of A/Ind05, stalk of A/PR8) | cH5/1PR | | | cH5/1 (head of A/Ind05, stalk of A/Cal09) | cH5/1Cal | | | cH9/1 (head of A/gf/HK99, head of A/Cal09) | cH9/1 | | | cH4/7 (Head of A/duck/Czech/1956, stalk of A/Shanghai/1/2013) | cH4/7 | |
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Note. All antigens were trimeric.
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