Improved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG

Table 4

FDR and specificity comparison with and without considering the strain subtype variations in the treatment groups comparisons at different settings.

Parameter settings		With	Without	With	Without
		FDR		Specificity
	0.25	0.1197	0.6732	0.9547	0.3133
	0.30	0.0826	0.6149	0.9614	0.3157
Setting 1	0.40	0.0610	0.5068	0.9567	0.3150
	0.50	0.0672	0.4152	0.9280	0.2900
	0.60	0.0260	0.3143	0.9600	0.3125
	0.75	0.0234	0.1830	0.9280	0.3280
	0.90	0.0055	0.0731	0.9500	0.2900
	0.40	0.0610	0.4709	0.9567	0.4067
	0.50	0.0672	0.3842	0.9280	0.3760
Setting 2	0.60	0.0260	0.2874	0.9600	0.3950
	0.75	0.0234	0.1629	0.9280	0.4160
	0.90	0.0055	0.0644	0.9500	0.3800
	0.25	0.1197	0.4781	0.9547	0.6947
	0.30	0.0826	0.4275	0.9614	0.6800
	0.40	0.0610	0.3068	0.9567	0.7050
	0.50	0.0672	0.2378	0.9280	0.6880
Setting 3	0.60	0.0260	0.1477	0.9600	0.7400
	0.75	0.0234	0.0809	0.9280	0.7360
	0.90	0.0055	0.0323	0.9500	0.7000
	0.25	0.1197	0.4877	0.9547	0.6827
	0.30	0.0826	0.4361	0.9614	0.6686
	0.40	0.0610	0.3377	0.9567	0.6600
Setting 4	0.50	0.0672	0.2636	0.9280	0.6420
	0.60	0.0260	0.1620	0.9600	0.7100
	0.75	0.0234	0.0931	0.9280	0.6920
	0.90	0.0055	0.0270	0.9500	0.7500

FDR = false discovery rate.