|
| Equation | Parameter | Description |
|
| | Growth rate of tumor-sensitive cells |
| Carrying capacity of tumor cells |
| Tumor cell death rate due to immune cells |
| μ | Mutation rate |
| Chemotherapy kill rate coefficient for tumor-sensitive cells |
| Radiotherapy kill rate coefficient for tumor-sensitive cells |
|
| | Growth rate of tumor-resistant cells |
| Chemotherapy kill rate coefficient for tumor-resistant cells |
| Radiotherapy kill rate coefficient for tumor-resistant cells |
|
| | Growth rate of normal cells |
| Carrying capacity of normal cells |
| k | Activation rate of tumor cells into normal cells |
| Critical size of tumor cells |
| Chemotherapy kill rate coefficient for normal cells |
| Radiotherapy kill rate coefficient for normal cells |
|
| s | Constant source of immune cells |
| d | Natural death rate of immune cells |
| Maximum immune response rate |
| Steepness of immune rate |
| Immune cells death rate due to tumor cell response |
| Chemotherapy kill rate coefficient for immune cells |
| Radiotherapy kill rate coefficient for immune cells |
|
| | Chemotherapy drug dose |
| Chemotherapy drug decay rate |
|
| | Radiotherapy drug dose |
| Radiotherapy drug decay rate |
|
