Research Article

Using Sacrificial Cell Spheroids for the Bioprinting of Perfusable 3D Tissue and Organ Constructs: A Computational Study

Figure 3

The initial state of computer simulations of a tissue construct made of endothelial (green) cells randomly dispersed in a hydrogel (106 cells/mL) and a branched chain of aggregates of sacrificial (yellow) cells. The 3D view of the construct is shown in the presence (a) and in the absence (b) of the embedding hydrogel; also, part of the construct is omitted to reveal the axial cross section of the sacrificial aggregates in the presence (c) and absence (d) of the hydrogel.
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